Autoimmune hemolytic anemia in patients with chronic lymphocytic leukemia is associated with IgVH status

Autoimmune hemolytic anemia in patients with chronic lymphocytic leukemia is associated with IgVH status.

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Autoimmune hemolytic anemia in chronic lymphocytic leukemia.

Restricted immunoglobulin VH region repertoire in chronic lymphocytic leukemia patients with autoimmune hemolytic anemia.

Between 10% and 25% of chronic lymphocytic leukemia (CLL) patients have episodes of autoimmune hemolytic anemia (AIHA) during the course of their disease. The anti-erythrocyte autoantibodies in most cases are polyclonal and express a different heavy chain isotype than the malignant clone, indicating that they are secreted by normal autoreactive B lymphocytes. To further investigate the pathogen...

Autoimmune hemolytic anemia in chronic granulocytic leukemia.

A UTOIMMUNE HEMOLYTIC ANEMIA may complicate a wide variety of diseases, among which are infectious diseases, “collagen” diseases, benign tumors, malignant tumors, lymphomas and Hodgkin’s disease.1’2 The lymphoproliferative disorders, especially chronic lymphatic leukemia, have often been associated with abnormal immunologic mechanisms. The myeloproliferative disorders are rarely associated with...

Two Cases of Chronic Hemolytic Anemia Associated with Spherocytosis

Two cases of hemolytic anemia with spherocy­tosis were investigated. lnspite of chronic hemolysis tl::crc was no radiological changes in flat bones. Ma­nagement and entity of spherocytosis is discussed m detail in this paper.